Biological Activity of Picrasma quassioides Extracts

Jung-Woo Chae1, Hye-Jin Park2, Sun-Ae Kang2,  Ju-Yeong Lee2, Bong-Jeun An3, Myung-Uk Kim4, Won-Seup Cha5, Young-Je Cho5*

1Gyeonggi-do Forest Environment Research Institute, Osan 447-290, Korea. 2School of Applied Bioscience, Kyungpook National University, Daegu 702-701, Korea. 3Department of Cosmeceutical, Daegu Hanny University, Gyeongsan, 712-715, Korea. 4Gyeongbuk Institute for Marine Bio-Industry, Uljin 767-813, Korea. 5School of Food science & Biotechnology / Food & Bio-Industry Research Institute, Kyungpook National University, Daegu 702-701, Korea

The extracts from Picrasma quassioides were studied for antioxidative activities and inhinbitory activities against angiotensin converting enzyme (ACE) and xanthine oxidase(XOase). Total phenolic compounds from Picrasma quassioides extracts were 2.7  and 2.8 mg/g in the water and 70% ethanol extracts of branch extracts and 15.8 and 16.2 mg/g in the water and 70% ethanol extracts of leaves extracts, respectively. DPPH radical scavenging activity by extracts from branch and leaves of Picrasma quassioides were each 70.32±1.26, 89.73±1.06, 92.41±2,93 and 79.65±0.95% in water and 70% ethanol extracts. ABTS radical scavenging activity by extracts from branch and leaves of Picrasma quassioides were 97.63±1.37, 98.75±0.65, 98.35±1.65 and 99.06±1.29% in water and 70% ethanol extracts. Antioxidant protection factor (PF) was determined the highest as 1.93±0.15 PF in water extracts from branch. TBARs inhibitory activity in 70% ethanol extracts from leaves was higher than that of water extracts at 200 ㎍/㎖ phenolic concentration. Inhibitory activity of Picrasma quassioides branch extracts against angiotensin converting enzyme (ACE) was higher as 80.49±2.64% in the 70% ethanol extract than captopril of 200㎍/㎖ concentration as 55.14±2.44%. The inhibitory activities against xanthin oxidase by Picrasma quassioides leaf extracts were observed as 84.76±6.90 and 85.20±4.27% in water and 70% ethanol extracts.